Temperature-absorption transition spectroscopy: a technique for estimating the relative charge densities on thiolated phosphate groups in nucleic acid analogues

Das, M.C.

Indian Journal of Biochemistry and Biophysics 26(1): 9-13

1989


ISSN/ISBN: 0301-1208
PMID: 2777316
Document Number: 334169
Various polynucleotides with well-defined sequences at low salt concentration have been studied using temperature-absorbtion transition spectroscopy to understand their conformations. It has been observed that the adopted technique can fairly estimate the relative charge densities at the thiolated phosphate groups in nucleic acid analogues at low salt concentrations.

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