Diagnostic value of radioimmunological analysis of CA-19-9 in the blood serum in cancer of the pancreas
Putseva, N.M.; Chebotareva, E.D.; Chernyĭ, V.A.; Tashchiev, R.K.
Klinicheskaia Khirurgiia 11: 15-17
1989
ISSN/ISBN: 0023-2130 PMID: 2625847 Document Number: 333548
The CA 19-9 antigen content was studied in 163 patients with pancreatic diseases by radioimmunologic method with the use of commercial test-kits ("Sorin", France). Pancreatitis was diagnosed in 67 patients, pancreatic cancer--in 23, cancer of the major duodenal papilla (MDP)--in 14, malignant neoplasms of the stomach, colon and rectum, liver--in 58. All the results were verified by morphologic studies. The control group included 22 donors. In patients with pancreatic cancer, the considerable increase in the CA 19-9 level was noted when compared with antigen content in the norm and in the other patients examined. The indices of CA 19-9 in pancreatitis don't differ from the normal ones. In MDP cancer and malignant tumours of other location with tumour invasion into the pancreas, the serum CA 19-9 level was increased.