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Antiviral activity in urine is attributable to ammonium salts

Baron, S.; Sabados, J.; McKerlie, M.L.; Coppenhaver, D.H.

Journal of Biological Regulators and Homeostatic Agents 3(2): 67-70

1989

ISSN/ISBN: 0393-974X
PMID: 2510466
Document Number: 333318
Urine exhibits antiviral activity in tissue culture against a number of viruses. We have characterized that antiviral activity in comparison with a number of antiviral substances which are known to be present in body fluids. We show here that the antiviral activity in urine cannot be due to the presence of contact-blocking virus inhibitor (CVI), or interferon. The findings support the conclusion that most of the antivirul activity in urine is qualitatively and quantitatively attributable to its content of ammonium salts.

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