Amiodarone
Smith, W.C.; Reddy, C.P.
Journal of the Louisiana State Medical Society Official Organ of the Louisiana State Medical Society 141(5): 35-38
1989
ISSN/ISBN: 0024-6921 PMID: 2659709 Document Number: 332101
Amiodarone is an antiarrhythmic agent with unique electrophysiological and pharmacokinetic properties and a wide spectrum of antiarrhythmic activity. Its clinical efficacy is not confined to ventricular arrhythmias but extends to supraventricular arrhythmias including those associated with Wolff-Parkinson-White Syndrome. Though a highly effective drug, amiodarone causes significant side effects. In this article, the electrophysiologic and pharmacokinetic properties, the clinical efficacy, and the adverse effects of amiodarone are reviewed.