Ciprofloxacin: a study of usage in pedal infections with case reports
Notari, M.A.; Mittler, B.E.
Journal of Foot Surgery 28(6): 521-523
1989
ISSN/ISBN: 0449-2544 PMID: 2630590 Document Number: 331798
Ciprofloxacin, an antibiotic of the quinolone class, has exhibited properties that may lead to frequent use in the febrile patient. Particularly important to the podiatrist is the bactericidal action of the drug on penicillinase producing Staphylococcus aureus and Pseudomonas species. Ciprofloxacin also kills many Gram-negative bacteria, and some anaerobic bacteria. Infections of this nature have been classically treated with parenteral antibiotics in a hospital setting. Ciprofloxacin has demonstrated, in clinical studies, the ability to kill these organisms in skin, soft tissues, and bone while using an oral route of administration. When considering cost-containment strategies in the patient with osteomyelitis, ciprofloxacin can cost between 50% to 80% less than parenteral therapy.