Ultrastructure of human adrenal glands at various periods of prenatal morphogenesis
Bogdanova, T.I.; Debelenko, L.V.
Arkhiv Anatomii Gistologii i Embriologii 96(4): 69-76
1989
ISSN/ISBN: 0004-1947 PMID: 2764742 Document Number: 331341
As demonstrates the electron microscopical investigation of the adrenals in human embryos and fetuses 6--32-week-old, at the age of 10--12 weeks glomerular and fasciculo-reticular zones are already differentiating. Subsequently, during following stages of the prenatal morphogenesis, when ultramicroscopical signs of the zonal belonging of cells and specific activity of steroid-synthesizing organells, the cortical reaction to the birth stress is manifested. Installation of the cells of the medullary substance takes place along nervous fibers, via paravasal and intravascular ways. Formation of the medullary substance by the time of birth is evidently not completed. Some critical estimations on the well known concept of the fetal cortex are presented. As the authors think, it needs to be recomprehended.