Long-term prognosis of the results of splenectomy in idiopathic thrombocytopenic purpura
Arendt, T.; Nizze, H.; Konrad, H.
Folia Haematologica 116(2): 337-342
1989
ISSN/ISBN: 0323-4347 PMID: 2475416 Document Number: 330988
The value of selected clinical and histological parameters for the prognosis of long-term results of splenectomies was investigated retrospectively in 50 patients with idiopathic thrombocytopenic purpura 4-14 years after surgery. Two parameters showed an association to the results of splenectomy, viz. spleen follicle size as well as site of thrombocytopenia degradation. Non-responders to splenectomy (n = 7) only turned up in spleen follicle hyperplasia, never in follicle normoplasia, however (p less than 0.01), four times more frequently in mainly extralienal thrombocyte degradation, also in predominantly lienal ones (p greater than 0.05).