Somatomedins: growth and differentiation factors. Clinical implications
Chatelain, P.; Nicolino, M.; De Parscau, L.; Saez, J.; Francois, R.
Pediatrie 44(4): 303-308
1989
ISSN/ISBN: 0031-4021 PMID: 2677972 Document Number: 330854
This review focuses on the action of somatomedins IGF-1 and IGF-2, and in particular the role of IGF-1 in cell multiplication and differentiation. A brief overview is given of the factors controlling IGF-1 flow rate expression in the tissues. Factors influencing IGF-1 plasma levels, i.e. age, and insufficiency or excess of growth hormone, are discussed.
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