Studies of lysozyme activity in the saliva of workers in the drug industry
Zajaczkowska-Białowas, L.; Nowicka, J.; Kuc, B.; Sibora, P.
Medycyna Pracy 40(5): 321-327
1989
ISSN/ISBN: 0465-5893 PMID: 2628700 Document Number: 330168
The aim of this study was to examine the lysozyme activity in saliva of pharmaceutic industry workers in whom pathologic changes in the oral cavity were previously diagnosed. The study was carried out in the Pharmaceutic Plant "Polfa" in Stargard Gdański at the departments of sulphonamides, acetylsalicylic acid and various syntheses. The study comprised 94 workers from whom resting saliva samples were collected 2-3 hours after breakfast. The lysozyme activity was determined using the modified Litwack method, while proteins were examined using the Lawry method. Our examinations have demonstrated a higher enzyme activity in pharmaceutic industry workers as compared to the control group. The highest lysozyme activity was recorded at the sulphonamides department.