Low density lipoprotein distribution by flotation characteristics in normal conditions and in dyslipoproteinemias
Medvedeva, N.V.; Morozkin, A.D.; Goroshkova, I.N.; Ruuge, E.K.; Shcherbakova, I.A.
Voprosy Meditsinskoi Khimii 35(3): 36-41
1989
ISSN/ISBN: 0042-8809 PMID: 2773382 Document Number: 329691
Distribution of low density (LDL; density range of 1.006-1.063), using the LDL flotation velocity in ultracentrifugation as a criterion, was studied in 4 groups of patients with coronary atherosclerosis (31 patients was examined, 24 of which were with angiographically confirmed coronary atherosclerosis): control group, patients with ischemic heart disease-with normal level of blood plasma lipids, with increased content of triglycerides and with decreased content of LDL cholesterol. The ratio of LDL particles with high hydration density was elevated in the LDL spectrum of all the patients examined. At the same time, each group of patients examined exhibited specific alterations in the LDL distribution spectra.