Bacterial meningitis with initial normal cerebrospinal fluid findings
Rosenthal, J.; Golan, A.; Dagan, R.
Israel Journal of Medical Sciences 25(4): 186-188
1989
ISSN/ISBN: 0021-2180 PMID: 2708023 Document Number: 329505
Seven pediatric patients with bacterial meningitis but with initial normal cerebrospinal fluid (CSF) findings are presented. They represent 6.5% of all cases with bacterial meningitis seen at our medical center during a 5-year period. In all cases, the duration of symptoms before the initial lumbar puncture was short (6-24 h). The case-fatality rate was 3/7 (43%) compared with 10/100 (10%) among children with abnormal initial CSF, despite early initiation of antibiotics. Bacterial meningitis with an initial normal CSF finding is not rare and may be associated with poor outcome.