Characteristics of viral hepatitis non-A, non-B with a fecal-oral mechanism of transmission of the infection in southern Uzbekistan
Favorov, M.O.; Kuzin, S.N.; Iashina, T.L.; Zairov, G.K.; Gurov, A.V.; Shavakhabov, S.S.; Buriev, A.I.; Zhantemirov, B.U.; Shakhgil'dian, I.V.; Ketiladze, E.S.
Voprosy Virusologii 34(4): 436-442
1989
ISSN/ISBN: 0507-4088 PMID: 2531498 Document Number: 328854
An increase in the incidence of viral hepatitis was observed in the autumn of 1986 in one of the districts of southern Uzbekistan. The clinico-epidemiological data and highly sensitive tests for hepatitis A (HA) and B (HB) markers showed the absence of HB infection in most of the patients and prevalence of HA among children. In 68.7% of the patients, non-A-non-B hepatitis with fecal-oral mechanism of transmission of the infection was diagnosed. The bulk of HnAnB patients consisted of adults of 20-29 years. Pregnant women experience severe forms of the disease. Solid-phase enzyme-immunoassays and immune electron microscopy revealed in one fecal specimen from patients the antigen of non-A-non-B hepatitis serologically identical to that causing a rise in the incidence in northern Turkmenia in 1984-1985.