Ten families of ankylosing spondylitis
Fu, X.; Wang, J.C.; Jia, Y.M.; Kang, Q.; An, J.B.
Chinese Medical Journal 102(9): 709-712
1989
ISSN/ISBN: 0366-6999 PMID: 2517085 Document Number: 328274
Twenty-two patients with ankylosing spondylitis (AS) from 10 families were studied with special attention to their clinical findings, HLA-B27 examinations and family histories. Results showed that HLA-B27 was positive in 19 and negative in 3. The hereditary relationship between ankylosing spondylitis and HLA-B27 in Chinese was similar to that in westerners. We consider that subjective symptoms and clinical findings are essential to early diagnosis of AS, but HLA-B27 examination and family history are supportive.