Effects of morphine and naloxone on pain sensitivity after radiation injuries in rats
Ignatov, I.D.; Abdrakhmanov, A.A.; Lashkul, N.N.; Zaĭtsev, A.A.
Biulleten' Eksperimental'noi Biologii i Meditsiny 108(10): 453-454
1989
ISSN/ISBN: 0365-9615 PMID: 2597759 Document Number: 327414
Radiation in doses 150 Gy induces different changes in pain sensitivity in rats by thermal (analgesia) and electrical (hyperalgesia) stimuli. Naloxone (0.1 and 1 mg/kg) and morphine (5 mg/kg) show, that analgesia is realized due to opioid mechanisms.
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