Historical role of endemic goiter in elucidating the importance of iodine nutrition, the function and control of thyroid gland, the structure of thyroid hormone, and the use of antithyroid drugs in thyrotoxicosis
Greer, M.A.
Endocrinologia Experimentalis 20(1): 9-16
1986
ISSN/ISBN: 0013-7200 PMID: 2422010 Document Number: 3268
This article briefly reviews how endemic goiter led directly to the critical studies: 1. established the role of iodine in thyroid economy, 2. the negative feedback of thyroid hormone on TSH secretion, 3. the structure of thyroid hormone, and 4. the discovery of antithyroid drugs and their utility in treating thyrotoxicosis.
Document emailed within 1 workday
Related Documents
Berger, H.; Glatzl, J.; Riccabona, G.; Haberfellner, H. 1973: The thyroid gland scintigram as a method for determination of the thyroid gland size in children from endemic goiter districts Acta Endocrinologica. Supplementum 179: 71-72Podoba, J.; Hnilica, P.; Srbecký, M.; Podobová, M. 1995: The effectiveness of iodine prophylaxis of endemic goiter in Slovakia from the viewpoint of physical and ultrasonographic examinations of the thyroid gland Bratislavske Lekarske Listy 96(11): 622-626
Mishra, A.K.; Agarwal, A. 2006: Clinical importance of solitary thyroid nodule of the thyroid in endemic goiter region Indian journal of medical sciences 60(6): 246-7; author reply 247-8
Zhu, X.Y.; Lu, T.Z.; Shi, Z.F.; Hou, M.T. 1981: Studies on endemic goiter and endemic cretinism in Guizhou: observations on iodine metabolism and pituitary thyroid axis functional status Chinese Medical Journal 94(9): 555-566
Bolotova, N.V.; Lisenkova, L.A.; Shchepliagina, L.A.; Glukhova, T.V.; Kruglov, A.V.; Perepelova, E.M. 1994: Echography of the thyroid gland in the diagnosis of endemic goiter Problemy Endokrinologii 40(4): 16-19
Ermans, A.M. 1984: Role of hypothalamo-hypophyseal control in the adjustment of thyroid function to iodine deficiency Bulletin et Memoires de l'Academie Royale de Medecine de Belgique 139(4): 236-247
Schöne, F.; Jahreis, G.; Lange, R.; Seffner, W.; Groppel, B.; Hennig, A.; Lüdke, H. 1990: Effect of varying glucosinolate and iodine intake via rapeseed meal diets on serum thyroid hormone level and total iodine in the thyroid in growing pigs Endocrinologia Experimentalis 24(4): 415-427
Mato, A.; Gippini, A.; Peino, R.; Gayoso, P.; Uriel, B. 1996: Differentiated carcinoma of the thyroid gland in an area of endemic goiter. Clinical study and prognostic correlation Anales de Medicina Interna 13(11): 537-540
Riccabona, G.; Bauer, H.; Lugger, L.J. 1973: Pathophysiologic findings in endemic goiter and normal thyroid glands in an endemic goiter district Acta Endocrinologica. Supplementum 179: 47-48
Fal'fushyns'ka, H.I.; Hnatyshyna, L.L.; Ocadchuk, D.V.; Shidlovs'kyĭ, V.O.; Stoliar, O.B. 2011: Metal-binding functions and antioxidant properties in human thyroid gland under iodine deficient nodular colloidal goiter Ukrains'kyi Biokhimichnyi Zhurnal 83(6): 92-97
Britton, R.S.; Koves, G.; Orrego, H.; Kalant, H.; Phillips, M.J.; Khanna, J.M.; Israel, Y. 1979: Suppression by antithyroid drugs of experimental hepatic necrosis after ethanol treatment. Effect on thyroid gland or on peripheral deiodination? Toxicology and Applied Pharmacology 51(1): 145-155
Klofanda, J.; Krska, Z.; Trca, S.; Krenek, M. 2000: Total removal of thyroid gland at the patients with malignant goiter, importance, problems and subsequent therapy Acta Universitatis Palackianae Olomucensis Facultatis Medicae 143: 89
Robiller, F. 1974: Function of the euthyroid budgerigar thyroid gland after application of iodine and TSH Archiv für Experimentelle Veterinarmedizin 28(1): 11-14
Kapitola, J.; Schüllerová, M.; Schreiberová, O.; Vilimovská, D. 1974: Endocrine effects on peripheral circulation in rats: effect of suppression of thyroid gland function and administration of dried thyroid gland Acta Universitatis Carolinae. Medica 20(7-8): 483-495
Korolev, I.N.; Nikulina, L.A.; Korovkina, E.G.; Bobkova, A.S. 1991: Morphofunctional shifts in the thyroid and liver and a change in the thyroid hormone level in the blood with the internal use of iodine-containing waters Voprosy Kurortologii Fizioterapii i Lechebnoi Fizicheskoi Kultury 5: 9-13
Lambrecht, W.; Raiński, J.; Zgrych, J.; Szmidt, M. 1985: Diagnostic methods in the evaluation of thyroid gland function in patients with goiter during preparation for surgery Wiadomosci Lekarskie 38(8): 584-588
Kehr, S.; Gastauer, R.; Winkler, G. 1985: Diabetes mellitus type I, thyroid gland autoimmunity, thyroid gland function and HLA status Monatsschrift Kinderheilkunde: Organ der Deutschen Gesellschaft für Kinderheilkunde 133(10): 738-742
Rabska-Pietrzak, B.; Lacka, K.; Krysińska, I.; Zamysłowska, H.; Bartkowiak, M.; Korman, E. 1995: Thyroid gland function in neonates with transient hyperthyrotrophinemia from a region of slight iodine deficiency Pediatria Polska 70(9): 745-752
Lietz, H.; Böcker, W. 1974: Structure and function of mesenchyma in the thyroid gland Verhandlungen der Deutschen Gesellschaft für Pathologie 58: 567
Wang, X.; Osiman, R.; Ma, F.; Guo, Y.; Tuhuti, H.; Zhao, H.; Abudunaiyimu, M.; Jin, X.; Wang, H.; Xing, S. 2015: Changes of thyroid function, thyroid antibodies and urinary iodine among permanent residents of Urumqi in Xinjiang Zhonghua Liu Xing Bing Xue Za Zhi 36(8): 811-814