Unresolved questions on the diagnosis of hepatitis in donors
Khersonskaia, R.Ia.; Zverkova, A.S.; Fedorovskaia, E.A.; Rogotskaia, L.T.; Zakharenko, N.I.
Voprosy Virusologii 33(6): 690-692
1988
ISSN/ISBN: 0507-4088 PMID: 3247688 Document Number: 326328
Clinico-laboratory characteristics of liver lesions occurring in 64 immune donors of blood plasma of 0(1) group are presented. The diseases ran as subclinical, latent, anicteric forms of hepatitis, and only in 5 persons as acute icteric hepatitis. In 50% of the patients there were signs of the disease becoming chronic: long-term increase in the blood serum of the activity of alanine aminotransferase, alkaline phosphatase, variations in bilirubin levels. Certain unresolved and disputable problems of etiological diagnosis of hepatitis in plasma donors, especially in differentiation of autoimmune hepatitis and non-A-non-B hepatitis are discussed.