Pathogenetic analysis of postoperative protein concentration and cell count of fibrin exudate in the anterior chamber of the eye with a posterior chamber lens
Tsurimaki, Y.; Sawa, M.; Shimizu, H.
Nippon Ganka Gakkai Zasshi 92(10): 1690-1695
1988
ISSN/ISBN: 0029-0203 PMID: 3213773 Document Number: 326248
The time course of changes in postoperative protein concentration and cell count in an anterior chamber was investigated in 59 eyes after senile cataract operations. The subjects underwent extracapsular cataract extraction, and 49 of them received implanation of a posterior chamber lens (PCL). Daily follow-up was performed from the first to the 7th postoperative day using a slit-lamp microscope and laser flare-cell meter, which was able to quantitatively mesure the protein concentration and cell count in an anterior chamber. With slit-lamp microscopy fibrin exudate was observed in 15 eyes (31%) among PCL implanted eyes and none among unimplanted eyes. The PCL implanted group was divided according into a fibrin (+) and a fibrin (-) subgroups. The mean protein concentration of the PCL implanted eyes was over 1,100 mg/dl in the first postoperative day and fell under 800 mg/dl in the second day. In the third day the concentration showed a reincrease in the fibrin (+) group and a gradual decrease in the fibrin (-) group. After the 4th day the concentration had kept over 1,200 mg/dl in the fiarin (+) and under 500 mg/dl in the fibrin (-). In the unimplanted eyes, no reincrease of protein concentration was observed. Statistical differences were calculated positively after the third day between the fibrin (+) and the other two groups (Mann-Whitney U-test; p < 0.05). The cell count also showed statistical differences between the fibrin (+) and the other two groups after the 5th day (Mann-Whitney U-test; p < 0.05), but reincrease in relation to the fibrin exudation was not observed. The appearance of fibrin exudate, which was preceded by the reincrease of the protein concentration, was thought to be the consequence of damage to the blood aqueous barrier.