Hereditary characteristics of enzyme deficiency and dermatoglyphics in congenital color blindness
Wu, L.Z.; Zeng, L.H.; Ma, Q.Y.; Xie, Y.J.; Chen, Y.Z.; Wu, D.Z.
Japanese Journal of Ophthalmology 32(2): 236-245
1988
ISSN/ISBN: 0021-5155 PMID: 3263528 Document Number: 324571
The hereditary characteristics of enzyme deficiency and dermatoglyphics in congenital color blindness (CCB) were studied. We propose that there is a linkage between the two loci on the X-chromosome determining CCB and glucose-6-phosphate dehydrogenase (G6PD), based on our study of a high incidence of G6PD deficiency in 156 male cases with CCB. The CCB gene is closely linked with that of G6PD deficiency from our pedigree investigations. The rise in the frequency of eight or more whorls, the low value of atd angle and the presenting rate of real palmar patterns of the thenar, hypothenar and I, areas presented the hereditary traits of congenital color blindness.