An autopsy case of parathyroid carcinoma with primary hyperparathyroidism
Ishigaki, H.; Sutoh, K.; Fukushi, A.; Kudoh, H.; Suga, M.; Gasa, K.; Boku, A.; Takebe, K.; Sekine, T.
Gan no Rinsho. Japan Journal of Cancer Clinics 34(8): 1007-1012
1988
ISSN/ISBN: 0021-4949 PMID: 3404653 Document Number: 321739
An autopsy case of a 72-year-old woman who was determined as having had a parathyroid carcinoma with primary hyperparathyroidism is reported. On autopsy, a tumor, measuring 6 X 3 X 2 cm, was found beneath the left lobe of the thyroid gland, adherent to the left recurrent nerve and the trachea, though there was no metastasis evident. The tumor was found to be lobulated on cross section inspection. Histologically, the tumor cells were arranged in trabecular and in solid patterns with fibrous bands. A few tumor cells showed mitosis. Invasions to the capsules and the blood vessels were found present. Immunohistochemically, the parathyroid hormone was found positive in the cytoplasm of the tumor cells. Otitis fibrosa generalisata, metastatic calcification, acute pancreatitis, and core pulmonale also were observed.