Opioid-serotoninergic dysregulation in the pathophysiology of Tourette's syndrome
Sandyk, R.; Bamford, C.R.
Functional Neurology 3(2): 225-235
1988
ISSN/ISBN: 0393-5264 PMID: 3042531 Document Number: 320428
In the following communication the major neurotransmitter systems postulated to be involved in the pathophysiology of Tourette's syndrome are discussed. Malfunctions of the opioid and serotoninergic systems are discussed regarding their role in the pathophysiology of the neuropsychological, behavioural and other manifestations of the disease.