Evaluation of somatic and intellectual development after deep hypothermic circulatory arrest in infants and children
Iwamoto, I.; Baba, N.; Uchida, N.; Matsuo, K.; Koga, Y.
Nihon Kyobu Geka Gakkai 36(2): 214-220
1988
ISSN/ISBN: 0369-4739 PMID: 3385258 Document Number: 320387
We evaluated somatic and intellectual development in two hundred infants and children who had undergone open cardiac surgery under deep hypothermic circulatory arrest in 15 years following surgery performed between 1970 and 1979. These patients were divided in two groups for the comparative studies: Group I; 148 patients performed open heart surgery under simple deep hypothermia without pump oxygenator. Group II; 52 patients performed open heart surgery under surface cooling combined with cardiopulmonary bypass. The following results were obtained. 1) In both groups, all patients did not show significant abnormality in global behavior. 2) Preoperatively, body height and weight in patients of both groups were lower than those of the values of Nagasaki infants and children survey in 1979 in average, but postoperatively, the patients in both groups showed poor development by age 15, therafter normal development was found in the both groups over 15 years old. 3) No major differences were found in intelligence scores among preoperative and postoperative patients of each groups, but in two patients of group II, circulatory arrest time over 60 minutes was seemed to be associated with a cause of their low IQ scores. As a result, it was concluded that deep hypothermia can be used safely as an important adjunct for open cardiac surgery in infants and children without fear of retarding in somatic and intellectual development.