Is there a role for simple hysterectomy after irradiation for bulky cervical carcinoma?
Tinga, D.J.; Bouma, J.; Hollema, H.; Oosterhuis, J.W.; Timmer, P.R.; Aalders, J.G.
European Journal of Gynaecological Oncology 9(3): 191-195
1988
ISSN/ISBN: 0392-2936 PMID: 3391189 Document Number: 319727
Twenty eight patients with bulky cervical carcinoma, who were treated by irradiation and simple hysterectomy, were studied. Eight of these patients had non-radical pre-operative irradiation. The patients had various FIGO-stages. The prognostic significance of morphologically intact tumor cells in the hysterectomy specimen and the relationship between pre-operative irradiation dosage, intact tumor cells and recurrences is discussed. Positive pelvic lymph-nodes obtained by sampling had more prognostic significance than intact tumor cells in the hysterectomy specimen. The role of adjunctive hysterectomy in local tumor control was not evident. Non-radical pre-operative irradiation proved to be inadequate.