Management of pleural effusion secondary to metastatic adenocarcinoma in a dog
Shapiro, W.; Turrel, J.
Journal of the American Veterinary Medical Association 192(4): 530-532
1988
ISSN/ISBN: 0003-1488 PMID: 3372304 Document Number: 318623
A 4-year-old spayed Collie-type dog was examined for pleural effusion secondary to metastatic adenocarcinoma with no identifiable primary tumour. For 48 weeks, chemotherapy and thoracenteses relieved the clinical signs associated with pleural effusion. At the 49th week, 5 mCi of chromic phosphate 32P suspension was injected into the right pleural space. Pleural effusion was not detected for 14 weeks after 32P administration (week 63). In week 64, 32P suspension was readministered by injecting 7.5 mCi into the right hemithorax and 2.5 mCi into the right hemithorax and 2.5 mCi into the left. Pleural effusion was again detected 3 weeks later (week 67), and the dog was treated with additional chemotherapy. Death, at week 72, was caused by disseminated intravascular coagulopathy.