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Stereological estimates of nuclear volume correlated with clinical stage and progression of prostatic cancer: clinical aspects

Jörgensen, P.E.; Berild, G.H.; Bruun, E.; Weis, N.; Nielsen, K.; Gundersen, H.J.

Scandinavian Journal of Urology and Nephrology. Supplementum 110: 131-135

1988

ISSN/ISBN: 0300-8886
PMID: 2460916
Document Number: 318489
Fifty-one transurethral prostatectomies were reviewed regarding the possible prognostic value of stereological estimation of cell nuclear volume in prostatic cancer. Patients with manifest cancer had a larger nuclear volume than those with incidental cancer, even though the two groups were matched concerning age and histological grade of the cancer. The nuclear volume was larger in patients with incidental cancer than in those with prostatic hyperplasia. Stereological estimation of nuclear volume may be a useful objective supplement to other prognostic parameters in prostatic cancer.

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