Azimexone and cysteine hydrazide in the treatment of allergic encephalomyelitis
Błaszczyk, B.; Giełdanowski, J.; Woźniak, M.; Dobryszycka, W.; Lemmel, E.M.; Katkiewicz, M.; Viljanen, M.
Archivum Immunologiae et Therapiae Experimentalis 36(3): 217-227
1988
ISSN/ISBN: 0004-069X PMID: 3266915 Document Number: 317200
In the course of allergic encephalomyelitis (EAE) in chickens, azimexone suppressed the production of the specific IgM immunoglobulins. Moreover, it decreased the level of heptoglobin and sialic acid but stimulated the activity of antitrypsin. It was also observed to reduce the production of the plasmatic cells in the spleen. L-cysteine hydrazide hydrochloride decreased the level of sialic acid in EAE; intensified the activity of trypsin inhibitor and exerted no effect upon the level of antimyelin antibodies.