Ultrastructural markers of renal tubular transport in rats under physiological conditions
Kidawa, Z.; Cieciura, L.; Trznadel, K.
Folia Histochemica et Cytobiologica 26(4): 209-216
1988
ISSN/ISBN: 0239-8508 PMID: 3220143 Document Number: 316847
Mitochondria of the proximal and distal tubules which are in different configurational states of epithelial cells and their surface - volume relationship of intercellular spaces and basal infolded channels were evaluated in rats. The evaluation was performed with stereological methods. The studies were carried out on 5 rats under physiological conditions using electron microscopy. Mitochondria within the proximal and distal tubules were found to occur in transitional states close to the orthodox state. However, mitochondria within the proximal tubules were in a higher energy state, closer to the orthodox state when compared with those within the distal tubules. Surface - volume parameters of intracellular spaces and basal infolded channels were unexpectedly higher than the relation to active ion transport as well as indiscernible permeabililty of the distal tubular basement membrane.