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Influence of anesthetic agents on intraspinal evoked potentials

Iida, H.; Tanahashi, T.; Ishiyama, T.; Uematsu, H.; Yamamoto, M.

Masui. Japanese Journal of Anesthesiology 37(2): 169-175

1988

ISSN/ISBN: 0021-4892
PMID: 3373726
Document Number: 315578
Recently spinal evoked potential have been used as a spinal monitor during thoracic- and neurosurgery. We studied the changes of intraspinal potentials by anesthetic agents in dogs. Two short-latency negative potentials were observed in this model. The first negative potential was named 1st-wave, and the following one 2nd-wave. Nitrous oxide and halothane did not affect 1st-wave amplitude, but apparently decreased 2nd-wave amplitude. The decrease in 2nd-wave amplitude was not reversed by naloxone. Fentanyl similarly decreased 2nd-wave amplitude, and the decrease in 2nd-wave amplitude was reversed by naloxone. Buprenorphine did not affect either 1st-wave or 2nd-wave amplitude at all. We conclude that the attention to the influence of anesthetic agents on spinal evoked potentials is essential when we use this technique as a spinal function monitor.

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