Azidothymidine-induced depression of murine hemopoietic progenitor cells
Bogliolo, G.; Lerza, R.; Mencoboni, M.; Saviane, A.; Pannacciulli, I.
Experimental Hematology 16(11): 938-940
1988
ISSN/ISBN: 0301-472X PMID: 3181343 Document Number: 314477
The toxicity of the antiviral drug 3'-azido-3'-deoxythymidine was studied in vivo on murine hemopoietic progenitor cells and peripheral blood cells. The drug induced a marked decrease of all tested populations, showing a severe toxicity on hemopoiesis.
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