Effects of the triphasic oral contraceptive on lipid and lipoprotein metabolism
Kirumbi, L.W.; Maina, F.W.; Sekadde Kigondu, C.B.; Mati, J.K.
Journal of Obstetrics and Gynaecology of Eastern and Central Africa 9(1): 23-29
1991
ISSN/ISBN: 1012-8867 PMID: 12316812 Document Number: 314335
The effects of the triphasic oral contraceptive (OC) ethinyl estradiol (EE) and levonorgestrel (LNG) on lipid and lipoprotein metabolism were evaluated in 97 black Kenyan women. Subjects were recruited from the Family Planning Clinic and were followed for 12 months. There was an increase in fasting levels of total cholesterol. These changes were not statistically significant. However, the triglyceride increase was statistically significant at 9 months and 12 months (p0.05). The high density cholesterol remained unchanged. Thus, this triphasic OC was found to have minimal effect on lipid and lipoprotein metabolism.