Effects on the relay-cells in the lateral geniculate nucleus and the retinal ganglion cells in experimental amblyopia
Miwa, M.
Nippon Ganka Gakkai Zasshi 92(1): 69-76
1988
ISSN/ISBN: 0029-0203 PMID: 3389263 Document Number: 314297
This paper reports an investigation of the morphological properties of retinal ganglion cells in visually deprived cats. Three kittens with unilateral lid closure two to three weeks after birth were reared for 12 .apprx. 24 months. After a certain period of deprivation, the area and density of the retinal ganglion cells in the central area and nearby portions of the retina were measured using methods reported in a previous paper. The area of the relay-cells constituting the A and Al laminae of the LGN of one cat were calculated in brain sections stained by Cresyl-Violet. The large-sized relay-cells (Y relay-cells) in the A and Al laminae of the LGN projecting from the amblyopic eye showed apparent atrophy. The Al laminae projected ipsilaterally from the amblyopic eye was more atrophied than the A laminae which projected contralaterally from the atrophic eye. The retinal ganglion cells (both X-cells and Y-cells) were not affected by the experimental amblyopia.