Skin involvement in Hodgkin's disease
Requena Caballero, L.; Sánchez López, M.; Requena Caballero, C.; Vázquez López, F.; Hernández Moro, B.
Medicina Cutanea Ibero-Latino-Americana 16(2): 106-110
1988
ISSN/ISBN: 0210-5187 PMID: 3050325 Document Number: 313935
We report a case of a previously diagnosed patient of Hodgkin's disease, nodular sclerosis type and IVLDB stage. This patient subsequently presented a dermatologic nodule. A specimen cutaneous biopsy was performed and the histopathologic study demonstrated a dermal infiltrate with many classic Reed-Sternberg giant cells. These findings were consistent with the skin involvement in Hodgkin's disease. Specific cutaneous lesions are rare in this lymphoma and therefore it may be argued that our patient had a lymphomatoid papulosis. However, the protracted clinical course would not support this concept, because the dermatologic lesion responded to chemotherapy and it is well-known that the clinical course of the lymphomatoid papulosis is unaffected by these treatments. We concluded that our patient is a case of specific skin involvement in Hodgkin's disease.