Radiation therapy in the extranodal non-Hodgkin's lymphoma of the maxillo-facial region
Horiuchi, J.; Shibya, H.; Matsumoto, S.; Kamiyama, R.
Gan no Rinsho. Japan Journal of Cancer Clinics 34(5): 619-630
1988
ISSN/ISBN: 0021-4949 PMID: 3385928 Document Number: 312409
An analysis was made on localized extranodal non-Hodgkin's lymphoma in the maxillo-facial region treated with radiation. Histopathological evaluation was reviewed by Rappaport classification and Working Formulation (WF). High grade histology of WF was rather frequent (32%) compared to Waldeyer's (NHL) (7%). Prognosis of the disease was highly influenced by histopathologic grade in WF; five-year survival rate was 100% with low grade, 65.6% with intermediate grade and 33.3% with high grade. Marginal relapse was rare after radiation dose of 30-50 Gy, however, there was a high incidence of bone and/or soft tissue relapses. Bone marrow biopsy and bone scintigram were useful examinations in the staging procedure of extranodal NHL.