Hereditary neuropathy with recurrent mononeuropathy (tomaculous neuropathy)
Serena, M.; Bardin, P.G.
Rivista di Neurologia 58(3): 97-105
1988
ISSN/ISBN: 0035-6344 PMID: 3175463 Document Number: 311080
Clinical and neurophysiological studies were carried out in 15 members out of 5 families affected by recurrent peripheral nerve and brachial plexus palsies. Nerve biopsy showed typical "tomacula". While in 3 families a slight development of the symptomatology was observed in the other 2 families there was an evolution toward a severe symmetric neuropathy. Motor and sensory conduction velocity were, in some cases, slowed even in clinically unaffected nerves. Electrophysiological changes were more important at entrapment sites. Such abnormalities could be found also in unaffected family members.