Pretreatment hormone levels in prostatic cancer
Haapiainen, R.; Rannikko, S.; Alfthan, O.; Adlercreutz, H.
Scandinavian Journal of Urology and Nephrology. Supplementum 110: 137-143
1988
ISSN/ISBN: 0300-8886 PMID: 3187401 Document Number: 310169
Pretreatment plasma concentrations of total testosterone, prolactin, and total estradiol-17 beta (E2) were measured in 123 prostatic cancer patients who were categorized into groups according to the UICC classification. Patients with intracapsular tumour without metastases had significantly higher (p less than 0.05) pretreatment total estradiol levels than those with more advanced disease. The patients were treated either by orchiectomy or estrogens. The mean follow-up time was 48 months. Higher pretreatment estradiol and testosterone levels were associated with better survival. Prolactin assays seemed to be of no value in this respect.