Activity of interferon beta in condylomata with dysplastic lesion of the uterine cervix
Puligheddu, P.; Marcello, C.; Medda, F.; Parodo, G.; Setzu, A.; Lecca, U.
European Journal of Gynaecological Oncology 9(2): 161-162
1988
ISSN/ISBN: 0392-2936 PMID: 3383896 Document Number: 308417
The effectiveness of interferone .beta. in the treatment of condylomata of cervico-vaginal tract associated with CINs was evaluated in 25 patients. Human fibroblastic interferon (IFN.beta.) was administered by intra and perilesional infiltration at a dosage of 3 .times. 106 IU/day for 5 consecutive days the first week and every other day the second. The treatment showed: complete regression in 61.76% of CIN I and 58.69% of CIN II; partial regression in 26.47% of CIN I and 21.73% of CIN II. The picture remained unvaried in 11.76% of CIN I and 19.56% of CIN II.