A technic for selection of antidotes to an acute lethal poisoning
Trouvé, R.; Nahas, G.
Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 182(4): 421-424
1988
ISSN/ISBN: 0037-9026 PMID: 2977962 Document Number: 307882
The dose of a toxic substance which is lethal to the rat within 15 min (LD100.15 min) and its specific antidotes are defined. Atropine, diazepam and nimodipine in sequential administration are effective antidotes to a LD100.15 min (1.5 mg/kg) of paraoxon, an anticholinesterase.
Document emailed within 1 workday
Related Documents
Daunderer, M. 1978: Therapy for poisonings--antidotes. 1. the ABC of poisoning treatment, antidotes (indications, dosage) Fortschritte der Medizin 96(25): 1313-1317Trouvé, R.; Nahas, G.G. 1990: Antidotes to lethal cocaine toxicity in the rat Archives Internationales de Pharmacodynamie et de Therapie 305: 197-207
Clarkson, T.W.; Magos, L.; Cox, C.; Greenwood, M.R.; Amin-Zaki, L.; Majeed, M.A.; Al-Damluji, S.F. 1981: Tests of efficacy of antidotes for removal of methylmercury in human poisoning during the Iraq outbreak Journal of Pharmacology and Experimental Therapeutics 218(1): 74-83
Gao, F.L.; Ding, Z.K.; Song, H.Q. 1988: Studies on antidotes for organophosphate poisoning synthesis and structure-activity relationship of bispyridinium salts Yao Xue Xue Bao 23(5): 336-342
Steiner, E.; Wiesel, M.; Gross, G.B.; Achek, S. 1990: Small intestine wash-out: technic and indications in acute severe chloroquine poisoning in underdeveloped surgical environments Annales de Chirurgie 44(5): 411-412
Jones, S.G.; Basinger, M.A.; Jones, M.M.; Gibbs, S.J. 1982: A comparison of diethyldithiocarbamate and EDTA as antidotes for acute cadmium intoxication Research Communications in Chemical Pathology and Pharmacology 38(2): 271-278
Cochrane, B.J.; Richmond, R.C. 1980: The effects of lethal selection on the EST-6 to PGM region of chromosome 3 in Drosophila melanogaster Genetics 96(2): 491-506
Janik-Kurylcio, S.; Dobrzańska, I.; Czuczwar, Z. 1973: Lethal aniline poisoning Polski Tygodnik Lekarski 28(32): 1241-1242
Parajua Pozo, J.L.; García Arcal, C.; González Martín, G.; Medina Santaolalla, P. 1985: Isoniazid poisoning at lethal doses Medicina Clinica 85(11): 473-474
Crippa, O.; Polettini, A.; Avato, F.M. 1990: Lethal poisoning by zipeprol in drug addicts Journal of Forensic Sciences 35(4): 992-999
Brodersen, H.P.; Korsten, S.; Larbig, D. 1995: The procedure for elimination in potentially lethal thallium poisoning Deutsche Medizinische Wochenschrift 120(38): 1301
Aniol-Strzyzewska, K. 1976: Accidental lethal poisoning of a newborn infant with boric acid Pediatria Polska 51(12): 1475-1477
Fauran, F.; Césaire, G.; Pellissier, C.; Goudote, J. 1970: A case of lethal poisoning by chloroquine. Analytical importance of metabolite detection Annales Pharmaceutiques Francaises 28(11): 667-674
Lebedev, I.G. 1986: Selection of the operative technic in inguinal hernia Vestnik Khirurgii Imeni I. I. Grekova 137(8): 133-136
Malmlund, H.O.; Gustafsson, L.L.; Magnusson, A.; Wallinder, H. 1990: A case of lethal theophylline poisoning. Slow-release preparation gave treacherous and late symptoms Lakartidningen 87(34): 2585-2588
Fuke, C. 2007: Proposal of an analytical pathway for the treatment of poisoning--8 lethal-level points to notice in analysis of postmortem specimens Chudoku Kenkyu: Chudoku Kenkyukai Jun Kikanshi 20(2): 155-158
Haarer, B.K.; Corbett, A.; Kweon, Y.; Petzold, A.S.; Silver, P.; Brown, S.S. 1996: SEC3 mutations are synthetically lethal with profilin mutations and cause defects in diploid-specific bud-site selection Genetics 144(2): 495-510
Sakamoto, T.; Yoshioka, T.; Shirakawa, Y.; Kamei, T.; Murata, A.; Asari, Y.; Okumura, T.; Endo, Y.; Shimazu, T.; Tomioka, J. 2007: Guidelines for the treatment of acute chemical poisoning-11-symptomatic therapy 4. Management of circulation for drug overdose and poisoning Chudoku Kenkyu: Chudoku Kenkyukai Jun Kikanshi 20(1): 75-80
Scribano, E.; Vitulo, F.; Raffaele, L.; Blandino, G. 1988: Optimization of the radiographic technic in parotid sialography. Experimental findings and clinical evaluation of the selection of the film-screen combination La Radiologia Medica 75(4): 335-338
Bakir, H.Y.; Sayed, F.G.; Rahman, S.A.; Hamza, A.I.; Mahmoud, A.E.; Galal, L.A.; Attia, R.A. 2009: Comparative study between non lethal and lethal strains of Plasmodium yoelii with reference to its immunological aspect Journal of the Egyptian Society of Parasitology 39(2): 585-593