The effect of sympathomimetic and sympatholytic drugs upon resting point of accommodation
Miwa, T.; Fukagawa, K.; Tokoro, T.
Nippon Ganka Gakkai Zasshi 92(7): 1235-1241
1988
ISSN/ISBN: 0029-0203 PMID: 3189100 Document Number: 307414
Accommodation in the darkness-dark focus of accommodation-was measured with Canon Autoref R1. The effect of sympathomimetic and sympatholytic drugs (1 epinephrine, timolol maleate) on the dark focus of accomodation was examined. It was recognized that the refractive power increased approximately 0.60 D in the darkness in 116 eyes of 59 subjects with an age range of 19 .apprx. 54 yrs. The degree of myopic shift was smaller with lower degrees of myopia. In 60 eyes of 30 subjects with an age range of 19 .apprx. 45, timolol maleate had no effect on the dark focus of accommodation. Whereas 1 epinephrine produced a significant hyperopic shift in the dark focus of accommodation.