Spontaneous thyroiditis in the obese strain of chickens. IV. The effect of thymectomy and thymo-bursectomy on the development of the disease
Wick, G.; Kite, J.H.; Witebsky, E.
Journal of Immunology 104(1): 54-62
1970
ISSN/ISBN: 0022-1767 PMID: 5460795 Document Number: 30365
The obese strain of White Leghorn chickens has spontaneous chronic thyroiditis characterized by infiltration with mainly large mononuclear cells, the occurrence of a greater number of germinal centres in the thyroid gland, and the presence of circulating thyroglobulin autoantibodies. Bursectomy on the day of hatching resulted in a decrease in the incidence and severity of the disease 7 weeks later.