A comparison of the PD35-sGaw and PD20-FEV1 in assessment of the effect of oral anti-allergic compounds on the immediate asthmatic response to inhaled allergen

Ollier, S.; Osman, J.; Cresswell, L.A.; Davies, R.J.

Annals of Allergy 59(2): 159-162

1987


ISSN/ISBN: 0003-4738
PMID: 2887132
Document Number: 303058
Assessment of two methods of measuring airway response to allergen challenge showed that results obtained using FEV1 correlated well with those obtained using sGaw irrespective of pre-treatment. Significantly smaller amounts of allergen were required to reduce the sGaw by 35% than to reduce the FEV1 by 20%, although both indices discriminated equally well between the effects of drugs on airway responses to challenge.

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