Prediction of therapeutic lithium dose: comparison and improvement of current methods
Rosenberg, J.G.; Binder, R.L.; Berlant, J.
Journal of Clinical Psychiatry 48(7): 284-286
1987
ISSN/ISBN: 0160-6689 PMID: 3110139 Document Number: 302475
The predictive value of two methods of predicting therapeutic lithium dose was evaluated in 19 patients. A single time point lithium level determination method, modified by the use of a 900-mg instead of a 600-mg test dose, was found to be a reliable and safe predictor. A mathematical model used for predictions was found to be moderately accurate but to generally predict a lower dose than was actually required.
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