Therapeutic pathomorphosis of bone tumors
Polonskaia, N.Iu.
Arkhiv Patologii 49(12): 17-20
1987
ISSN/ISBN: 0004-1955 PMID: 3328592 Document Number: 301495
A comparative study of therapeutic pathomorphosis of bone tumors has shown that radiosensitive and radioresistant tumors differ in the time-course and nature of radiation-induced pathomorphosis. In radiosensitive tumors, the resultant changes arise earlier, are more strongly marked, and, as a rule, necrosis of the tumor with its replacement with fibrous tissue is observed. In radioresistant tumors, signs of radiation pathomorphosis appear later, "therapeutic giants" are typically seen to appear, and the direction in which tumor cells differentiate may change.