Cyclic nucleotides during radiotherapy of breast cancer

Lozinskaia, I.N.; Iakimova, T.P.

Voprosy Onkologii 33(8): 58-62

1987


ISSN/ISBN: 0507-3758
PMID: 2820147
Document Number: 299948
Levels of cAMP and cGMP were higher in breast cancer tissue as compared with benign tumors. Large-fraction irradiation was followed by a decrease in cGMP concentration matched by a rise in cAMP/cGMP ratio in cases of radiosensitive tumors. Small-fraction treatment did not affect cyclic nucleotide levels. Radiotherapy was followed by a decrease in initially raised blood plasma cyclic nucleotide concentration.

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