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Clinical experience using streptodecase in the prehospital stage of treatment of acute myocardial infarct

Mirrakhimov, M.M.; Baltabaev, T.B.; Tsoĭ, N.L.

Kardiologiia 27(2): 21-24

1987

ISSN/ISBN: 0022-9040
PMID: 3573519
Document Number: 298256
The effects of prehospital streptodecase administration on clinical course, pattern of necrosis formation, myocardial contractility and blood coagulation were studied in 15 patients with acute myocardial infarction. Patients to whom thrombolytic and anticoagulant therapy was contraindicated made up the control group. A single intravenous jet injection of the total streptodecase dose (3,000,000 U) is well tolerated by patients with acute myocardial infarction without preliminary testing. Prehospital use of the drug contributes to rapid stabilization and limitation of progressive myocardial necrosis, and improves thereby the clinical course of the disease.

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