Prevalence of Rett syndrome in Switzerland
Boltshauser, E.; Künzle, C.
Helvetica Paediatrica Acta 42(5-6): 407-411
1987
ISSN/ISBN: 0018-022X PMID: 3502625 Document Number: 298180
In an extensive survey, 35 cases of Rett syndrome born in Switzerland were found. Only 5 probands were older than 20 years; the oldest subject was 37. The prevalence for 1967-1982 was 0.41/10,000 (= 1:24,600) girls. This is considered a minimum prevalence since complete ascertainment was not possible by this investigation. Prevalence figures from southern Sweden and west of Scotland are higher (approximately 1:15,000). Rett syndrome is apparently responsible for a considerable proportion of girls with neurodegenerative disorders.