Hepatotoxicity of mebendazole. Relationship with serum concentrations of the drug
Bekhti, A.; Pirotte, J.
Gastroenterologie Clinique et Biologique 11(10): 701-703
1987
ISSN/ISBN: 0399-8320 PMID: 3692093 Document Number: 298015
We report the case of a 47-year-old female patient, suffering from multiple hydatid cysts of the liver, in whom hepatitis developed after mebendazole treatment. Clinical manifestations of hypersensitivity were absent. A correlation was found between serum mebendazole concentrations and the degree of cytolysis; this is compatible with a direct hepatotoxic effect of mebendazole.
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