Screening for osteomalacia in elderly patients with femoral neck fractures
Wilton, T.J.; Hosking, D.J.; Pawley, E.; Stevens, A.; Harvey, L.
Journal of Bone and Joint Surgery. British Volume 69(5): 765-768
1987
ISSN/ISBN: 0301-620X PMID: 3680338 Document Number: 297809
In this study 201 elderly patients with femoral neck fractures were compared with 30 osteomalacic patients with the same injury. Hypocalcaemia and a raised alkaline phosphatase level are common biochemical abnormalities in elderly patients with femoral neck fractures. In only a minority of patients, however, were they associated with histologically proven osteomalacia. By using the combination of hypocalcaemia and a raised alkaline phosphatase it is possible to identify a subgroup (approximately 10% of all admissions) in whom osteomalacia is relatively likely.