Radiation treatment for thymoma in a dog
Hitt, M.E.; Shaw, D.P.; Hogan, P.M.; Lennon, V.A.; Amann, J.F.
Journal of the American Veterinary Medical Association 190(9): 1187-1190
1987
ISSN/ISBN: 0003-1488 PMID: 3583897 Document Number: 297166
A 10-year-old Toy Poodle was admitted for evaluation of a chronic cough caused by a cranial mediastinal mass. The mass was diagnosed, by needle biopsy, as a thymoma. Detection of serum acetylcholine receptor antibodies suggested that the dog had subclinical myasthenia gravis. The dog underwent orthovoltage radiation treatment, which resulted in an approximate 60% reduction in tumour mass and freedom from clinical signs for 6 months. Concurrent use of prednisolone may have been associated with disappearance of the acetylcholine receptor antibodies.