Osteonecrosis following radiotherapy in carcinoma of the uterus and pediatric tumors
Sakurai, T.; Nishio, M.; Kagami, Y.; Narimatsu, N.; Morita, K.; Masuda, K.; Hoshino, F.
Gan no Rinsho. Japan Journal of Cancer Clinics 33(10): 1193-1198
1987
ISSN/ISBN: 0021-4949 PMID: 3669313 Document Number: 296948
Osteonecrosis following radiation therapy in 611 Patients with uterine cancer and 41 patients with pediatric tumor were studied. The 5- and 10-year cumulative bone injury rate after radiation therapy in uterine cancer was 4% and 15.6%, respectedly. Patients who are older than 60 years of age showed high occurrence of radiation bone injury. Otherwise, severe aletrations in shape and complete arrest of growth in irradiated growing bone were observed of even with small doses of 1600 cGy in the lower age level (0-3 age of years) at the time of treatment.