Chlamydia infection in Reiter's syndrome

Martinov, S.P.; Popov, G.W.; Dimitrov, K.D.

Zeitschrift für Hautkrankheiten 62(3): 216-219

1987


ISSN/ISBN: 0301-0481
PMID: 3495078
Document Number: 296714
We report on 129 patients (109 females, 21 males) clinically suspect of Reiter's syndrome (RS). 52 (48%) of the patients were positive for Chlamydia trachomatis. In 39.8% of the patients, we found antibodies against chlamydial complement with the titers 1:4 to 1:16. The titers 1:16 and higher were present in 33.3% of the men and in 22.2% of the women. Direct electron microscopy of urethral biopsies and synovial fluids revealed chlamydial elementary and initial bodies in 54.1% of the cases. Cytological investigations showed chlamydial inclusions in 38% of the patients. One strain of C. trachomatis could be isolated from urethral samples of two men in chicken embryos. HLA-B27 antigen was found in 86% of the patients positive for Chlamydia and in 50% of those negative for Chlamydia.

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