Pneumonia in pigs induced by intranasal challenge exposure with pseudorabies virus and Pasteurella multocida
Fuentes, M.C.; Pijoan, C.
American Journal of Veterinary Research 48(10): 1446-1448
1987
ISSN/ISBN: 0002-9645 PMID: 3674553 Document Number: 294447
The interaction between pseudorabies virus (PRV) and Pasteurella multocida was investigated to determine whether single or combined infections result in pneumonia in 6- to 7-week-old pigs. The effect of the PRV-P multocida challenge exposure on feed consumption, rate of gain, and extent of pneumonic lesions appeared dependent on the PRV dose; however, pneumonic lesions were of bacterial pneumonia. Pigs inoculated with a virulent strain of PRV plus P multocida developed severe pneumonia, whereas pigs given PRV only did not develop pneumonia. Modified-live PRV vaccine had no effect on the occurrence of pneumonia. Average daily gain was most depressed in pigs given the highest dose of virulent PRV plus P multocida.